Burkitt Leukemia With Precursor B-Cell Immunophenotype and Dual Translocation of t(14;18) and t(8;14) in a Child: Case Report and Review of the Literature


Odaman A. I. , Bayram C., Koc B. , Ersoy G., Uysalol E. P. , Aki H., ...More

JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, vol.42, no.1, 2020 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 42 Issue: 1
  • Publication Date: 2020
  • Doi Number: 10.1097/mph.0000000000001354
  • Title of Journal : JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY

Abstract

Background: Burkitt leukemia (BL) with the precursor B-cell immunophenotype is a rarely reported condition. The prognosis of such patients is similar to that of classic BL. However, the combination of chromosomal translocations associated with bcl-2 and c-myc rearrangement has a poor prognosis.