An association between mesial temporal lobe epilepsy with hippocampal sclerosis and human leukocyte antigens


Ozkara C. , ALTINTAS A., YILMAZ E., ESKAZAN E., ERKOL G. , OZYURT E., ...Daha Fazla

EPILEPSIA, cilt.43, ss.236-239, 2002 (SCI İndekslerine Giren Dergi) identifier identifier identifier

Özet

Purpose: Mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE-HS) is one of the medically intractable epilepsies that may be remediable with surgery. Although the pathogenesis of HS still remains obscure, genetics may play a role as a predisposing factor, with the genetically controlled immune system as one of its aspects. Our aim in this study was to investigate whether there is any association between human leukocyte antigens (HLAs) that are related to chromosome 6 and this specific type of epilepsy.