An association between mesial temporal lobe epilepsy with hippocampal sclerosis and human leukocyte antigens.


Ozkara C. , ALTINTAS A., YILMAZ E. , ESKAZAN E., ERKOL G. , OZYURT E., ...More

Epilepsia, vol.43, no.3, pp.236-9, 2002 (Journal Indexed in SCI Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 43 Issue: 3
  • Publication Date: 2002
  • Doi Number: 10.1046/j.1528-1157.2002.13401.x
  • Title of Journal : Epilepsia
  • Page Numbers: pp.236-9

Abstract

Purpose: Mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE-HS) is one of the medically intractable epilepsies that may be remediable with surgery. Although the pathogenesis of HS still remains obscure, genetics may play a role as a predisposing factor, with the genetically controlled immune system as one of its aspects. Our aim in this study was to investigate whether there is any association between human leukocyte antigens (HLAs) that are related to chromosome 6 and this specific type of epilepsy.