COX-2 GENE VARIANTS IN BIPOLAR DISORDER-I


ÖZDEMİRCAN A. , DAŞDEMİR S., KÜÇÜKALİ C. İ. , Bireller E. S. , Ozturk H., ÇAKMAKOĞLU B.

PSYCHIATRIA DANUBINA, cilt.27, sa.4, ss.385-389, 2015 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 27 Konu: 4
  • Basım Tarihi: 2015
  • Dergi Adı: PSYCHIATRIA DANUBINA
  • Sayfa Sayıları: ss.385-389

Özet

Background: Bipolar disorder-I (BD-I) is a complex illness, and multiple genes and environmental factors determine its pathogenesis. Several studies have ascertained that BD-I and inflammation are linked through shared genetic polymorphisms and gene expression, as well as altered cytokine levels. COX-2 gene polymorphisms affecting COX-2 levels may be associated with BD-I by altering the inflammatory response.