Involvement of prostaglandin F-2 alpha in preeclamptic human umbilical vein vasospasm: a role of prostaglandin F and thromboxane A(2) receptors


Topal G., Foudi N., Uydes-Dogan B. S. , Cachina T., Kucur M. , Gezer A. , ...Daha Fazla

JOURNAL OF HYPERTENSION, cilt.28, ss.2438-2445, 2010 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 28 Konu: 12
  • Basım Tarihi: 2010
  • Doi Numarası: 10.1097/hjh.0b013e32833e868f
  • Dergi Adı: JOURNAL OF HYPERTENSION
  • Sayfa Sayıları: ss.2438-2445

Özet

Objective Preeclampsia is characterized by hypertension and proteinuria developing after 20 weeks of gestation. Increased vasoconstriction can be one of the major underlying pathophysiological event in this syndrome. We examined the role of vasoconstrictor prostanoid, prostaglandin F-2 alpha (PGF(2 alpha)) in preeclamptic and normotensive human umbilical veins.