Abuse and addiction to opioids, including prescription painkillers, heroin and synthetic
opioids such as fentanyl, buprenorphine, constitute a serious crisis that affects public health
and has economic repercussions.1 Naltrexone implants are effective tools used in hospital
environments and they can not only save patient´s lives but also maintain a prolonged
effect, free of relapse and with better therapeutic adherence. The aim of this study is to
describe that the management protocol of acute abstinence symptoms in patients with a
history of opioid use prior to naltrexone implant placement.