Estimating the resistivity of the interior fluid of red blood cells using Fricke's equation


Ulgen Y., SEZDİ M.

Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings, cilt.5, ss.2112-2115, 1997 (Diğer Kurumların Hakemli Dergileri) identifier

  • Cilt numarası: 5
  • Basım Tarihi: 1997
  • Dergi Adı: Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
  • Sayfa Sayıları: ss.2112-2115

Özet

Multifrequency (1kHz-1MHz) impedance of human blood, from 8 donors, for the hematocrit range from 36% to 43.5%, is measured using the true four-probe technique. Cole-Cole parameters, that are characteristic of blood, are used to model the equivalent electrical circuit. Results are then applied to Fricke's theory of suspension of particles at f → 0 and f → ∞. Fricke's equation, so far, has been widely used at f → 0 in determining the shape factor for red cells or the hematocrit of blood samples. In this paper, it is shown that, solution of Fricke's equation of suspension at f → ∞ can be used in calculating the inside resistivity ρc of red cells. We suggest that ρc should replace the Cole-Cole parameter ρi. This parameter, together with Cole-Cole parameters might be a potential index for evaluating blood in clinical applications.