Correlation between the AHCPR (Agency for Health Care Policy and Research) risk stratification and angiographic morphology in non-ST-segment elevation acute coronary syndrome

Yildiz A., Pehlivanoǧlu S., Gürmen T., Coşkun U., Kiliçkesmez K. O. , Başkurt M., ...Daha Fazla

Turk Kardiyoloji Dernegi Arsivi, cilt.39, sa.2, ss.105-113, 2011 (SCI Expanded İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 39 Konu: 2
  • Basım Tarihi: 2011
  • Doi Numarası: 10.5543/tkda.2011.00910
  • Dergi Adı: Turk Kardiyoloji Dernegi Arsivi
  • Sayfa Sayıları: ss.105-113


Objectives: Risk stratification in acute coronary syndromes is an important diagnostic tool guiding future therapy. We evaluated the correlation between the AHCPR (Agency for Health Care Policy and Research) risk classification and angiographic morphology in patients with non-ST-segment elevation acute coronary syndrome (NSTE-ACS). Study design: A total of 163 patients hospitalized with the diagnosis of NSTE-ACS were prospectively enrolled. All the patients underwent AHCPR risk analysis followed by coronary angiography. Based on the AHCPR system, the patients were classified as low (n=25, mean age 55±10 years), intermediate (n=55, mean age 58±10 years), and high (n=83, mean age 61±11 years) risk groups. Results: The three groups were similar with regard to gender, age, and coronary heart disease risk factors (p>0.05). Comparison of the high-risk group with intermediate+low-risk group with regard to lesion morphology showed significantly higher rates of complex lesions (31.9% vs. 4.0%, p=0.001), total occlusion (23.2% vs. 0%, p=0.001), and intracoronary thrombosis (13% vs. 2%, p=0.02) in the high-risk group. In univariate analysis, high risk was significantly associated with the presence of complex lesion, total occlusion, intracoronary thrombosis, and TIMI flow