Evaluation of Dual Therapy in Real Life Setting in Treatment-Naive Turkish Patients with HCV Infection: A Multicenter, Retrospective Study


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Gurbuz Y., Tulek N. E. , Tutuncu E. E. , Koruk S. T. , AYGEN B., DEMİRTÜRK N., ...More

BALKAN MEDICAL JOURNAL, vol.33, no.1, pp.18-26, 2016 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 33 Issue: 1
  • Publication Date: 2016
  • Doi Number: 10.5152/balkanmedj.2015.15859
  • Title of Journal : BALKAN MEDICAL JOURNAL
  • Page Numbers: pp.18-26
  • Keywords: Hepatitis C, peginterferon alpha-2a, peginterferon alpha-2b, ribavirin, therapy, CHRONIC HEPATITIS-C, SUSTAINED VIROLOGICAL RESPONSE, ALPHA-2B PLUS RIBAVIRIN, PEGINTERFERON ALPHA-2A, HEPATOCELLULAR-CARCINOMA, INSULIN-RESISTANCE, COMBINATION THERAPY, TOLERABILITY, MANAGEMENT, DIAGNOSIS

Abstract

Background: Before the introduction of direct-acting antivirals in the treatment of chronic hepatitis C patients, the combination of peginterferon alpha and ribavirin was the standard therapy. Observational studies that investigated sustained virological response (SVR) rates by these drugs yielded different outcomes.