Cytogenetic Studies of Chromosome Abnormalities in Thyroid Cancer Patients Before and After Iodine-131 Treatment

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Oden S., Atasoy S., Demir M., Deviren A.

BEZMIALEM SCIENCE, cilt.7, sa.2, ss.118-123, 2019 (ESCI İndekslerine Giren Dergi) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 7 Konu: 2
  • Basım Tarihi: 2019
  • Doi Numarası: 10.14235/bas.galenos.2018.2571
  • Sayfa Sayıları: ss.118-123


Objective: Thyroid cancer is among the most common endocrine malignancies. Initial management consists surgery and ablation. I-131,which is used to damage surgically unremoved thyroid tissue or treat metastases, is a source for ionizing radiation (IR), also generates potential mutagenic and carcinogenic effects. The purpose of research is to investigate the damage on chromosomes at the I-131 treatment of thyroid cancer patients exposed to the same dose of genotoxic agent.