Interleukin 17 alone is not a discriminant biomarker in early demyelinating spectrum disorders


Lebrun C., Cohen M., Pignolet B., Seitz-Polski B., Bucciarelli F., Benzaken S., ...Daha Fazla

JOURNAL OF THE NEUROLOGICAL SCIENCES, cilt.368, ss.334-336, 2016 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 368
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1016/j.jns.2016.07.052
  • Dergi Adı: JOURNAL OF THE NEUROLOGICAL SCIENCES
  • Sayfa Sayıları: ss.334-336

Özet

Background: Radiologically isolated syndrome (RIS) is a sub clinical demyelinating neurological disorder and to date no biomarker that triggers the seminal event has been identified. As for multiple sclerosis (MS), disease activity and clinical course are unpredictable. In MS, exploratory studies reported increased IL-17 levels in CSF but results in detecting IL-17 in serum at different stage of the disease are controversial.