Gender specific association of ABCA1 gene R219K variant in coronary disease risk through interactions with serum triglyceride elevation in Turkish adults


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Coban N., Onat A., Bayrak E. K. , Gulec C., Can G. , Unaltuna N. E.

ANATOLIAN JOURNAL OF CARDIOLOGY, cilt.14, ss.18-25, 2014 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 14 Konu: 1
  • Basım Tarihi: 2014
  • Doi Numarası: 10.5152/akd.2013.234
  • Dergi Adı: ANATOLIAN JOURNAL OF CARDIOLOGY
  • Sayfa Sayısı: ss.18-25

Özet

Objective: ATP binding cassette transporter A1 (ABCA1) controls the reverse cholesterol transport. Some ABCA1 variants are correlated with serum high-density lipoprotein cholesterol (HDL-C) and other lipid concentrations. We aimed to explore the relationship of ABCA1 gene with both the lipid profile and coronary heart disease (CHD) risk.