High-dose piracetam is effective on cerebellar ataxia in a patient with cerebellar cortical atrophy


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Vural M. , Ozekmekci S., Apaydin H. , Altinel A.

MOVEMENT DISORDERS, cilt.18, ss.457-459, 2003 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 18 Konu: 4
  • Basım Tarihi: 2003
  • Doi Numarası: 10.1002/mds.10364
  • Dergi Adı: MOVEMENT DISORDERS
  • Sayfa Sayısı: ss.457-459

Özet

We describe a patient with cerebellar ataxia of degenerative nature who was administered high-dose piracetam in a single-blind trial. Piracetam was demonstrated to be highly effective on tandem gait and gait ataxia in daily doses of 60 g. We suggest piracetam has a potential anti-ataxic effect in human cerebellar ataxia when used in considerably higher doses than those indicated for other purposes. (C) 2003 Movement Disorder Society.

We report on a patient with spontaneous and stimulus-

sensitive myoclonic jerks and dystonia of the right leg that

had been present since infancy. Magnetic resonance imaging

showed a linear area of gliosis confined to the left posterolateral

putamen. This is the first report of focal myoclonus-dystonia of

the lower limb secondary to a putaminal lesion.