Gender-modulated impact of apolipoprotein A5 gene (APOA5)-1131T > C and c.56C > G polymorphisms on lipids, dyslipidernia and metabolic syndrome in Turkish adults


Komurcu-Bayrak E., Onat A., Poda M., Humphries S. E. , Palmen J., Guclu F., et al.

CLINICAL CHEMISTRY AND LABORATORY MEDICINE, cilt.46, ss.778-784, 2008 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 46 Konu: 6
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1515/cclm.2008.161
  • Dergi Adı: CLINICAL CHEMISTRY AND LABORATORY MEDICINE
  • Sayfa Sayısı: ss.778-784

Özet

Background: Apolipoprotein A5 (APOA5) gene polymorphisms are usually associated with plasma triglyceride levels. We evaluated the relationship of the APOA5 -1131T > C and c.56C > G polymorphisms [single nucleotide polymorphism (SNP)] with serum lipids, dyslipidemia [low high-density lipoprotein (HDL)/high triglyceride] and the risk for metabolic syndrome (IMS) in the Turkish Adult Risk Factor study.