Helicobacter pylori infection in children: Evaluation of complaints, endoscopic findings, diagnostic methods and post-treatment eradication rates Çocuklarda helicobacter pylori enfeksiyonu: Yakinma, endoskopik bulgu, tani yöntemleri ve tedavi sonrasi eradikasyon oranlarinin deǧerlendirilmesi


Doǧan Y., BARIŞ S., Erkan T., Önal Z., Usta M., Çokuǧraş F. Ç. , ...Daha Fazla

Turk Pediatri Arsivi, cilt.42, sa.3, ss.98-102, 2007 (SCI Expanded İndekslerine Giren Dergi) identifier

  • Cilt numarası: 42 Konu: 3
  • Basım Tarihi: 2007
  • Dergi Adı: Turk Pediatri Arsivi
  • Sayfa Sayıları: ss.98-102

Özet

Aim: This study aims to evaluate symptoms, endoscopic findings, diagnostic test results of cases with Helicobacter pylori gastritis, the treatment they have received and post-treatment eradication rates. Material and Method: Files of cases, who had undergone endoscopy and diagnosed as Helicobacter pylori gastritis in their biopsy samples taken between 1997-2005, were retrospectively evaluated. Age, sex, initial complaints, diagnostic tests, endoscopy findings, treatment methods and post-treatment follow-up results of cases were recorded. Results: Out of a total of 239 cases, 129 (54%) were males and 110 (46%) were females, with an average age of 10±3.2 years. There were complaints about abdominal cramps in 197 (82.4%) of cases, bloody vomiting and/or blood in stools in 55 (23%), and vomiting in 49 (20.5%). Among cases who had undergone endoscopy, 176 (73.6%) had antral nodularity, 24 (10%) had antral hyperemia, 31 (13%) had gastric ulcer, 31 (13%) had hyperemia in duodenal mucosa and 3 (1.2%) had duodenal ulcer. Anti-Helicobacter pylori IgG, Helicobacter pylori stool antigen and gastric biopsy culture were positive, respectively, in 79.3% (96/121), 61.1% (44/63) and 38.5% (15/39) of the cases. 224 cases (93.7%) had received treatment. Forty-four patients were lost to follow-up. Helicobacter pylori was eradicated in 152 (84.4%) of the 180 patients who came for follow-up. Conclusions: Abdominal pain is a common complaint in cases diagnosed as helicobacter pylori infection. While histological evaluation and culture are gold standards among the diagnostic tests, frequent failure of growth of Helicobacter pylori in culture is an important problem. Moreover, eradication cannot be achived in a considerable number of cases despite triple treatment.