This study was conducted for the purpose of testing the validity and reliability of the Turkish version of the Clinical Stress Questionnaire, which was developed to examine the stress that nursing students experience in their first clinical experiences that are threatening or challenging. The study sample was comprised of 80 first-year nursing students who had their first clinical practice experience. Internal consistency of the total questionnaire was Cronbach's alpha = 0.70 and the factor analysis supported the original construct. Based on these results the Turkish version of the Clinical Stress Questionnaire can be used as a valid and reliable instrument. (C) 2007 Elsevier Ltd. All rights reserved.