The effect of fluoxetine on ischemia-reperfusion after aortic surgery in a rat model


Guner I. , Yaman M. O. , Aksu U., Uzun D., Erman H., Inceli M., ...Daha Fazla

JOURNAL OF SURGICAL RESEARCH, cilt.189, ss.96-105, 2014 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 189 Konu: 1
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1016/j.jss.2014.02.033
  • Dergi Adı: JOURNAL OF SURGICAL RESEARCH
  • Sayfa Sayıları: ss.96-105

Özet

Background: Aortic ischemia-reperfusion (IR) is an important factor in the development of postoperative acute lung injury after abdominal aortic surgery. The aim of the present study was to examine the effect of fluoxetine (Flx), a selective serotonin reuptake inhibitor widely used as a preoperative anxiolytic, on lung injury induced by abdominal aortic IR in rats.