Combined effect of parathyroid hormone and strontium ranelate on bone healing in ovariectomized rats


GOKER F., Ersanli S., Arisan V., Cevher E., Guzel E. E. , Issever H., ...Daha Fazla

ORAL DISEASES, cilt.24, ss.1255-1269, 2018 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 24 Konu: 7
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1111/odi.12895
  • Dergi Adı: ORAL DISEASES
  • Sayfa Sayıları: ss.1255-1269

Özet

ObjectiveParathyroid hormone (PTH) enhances bone healing. Strontium ranelate (SR) is an antiresorptive agent that increases bone formation. Reports about combined effects of PTH and SR on local bone regeneration in osteoporotic subjects are limited. We aimed at investigating the efficacy of PTH and SR for promoting new bone formation in critical-sized defects of ovariectomized rats.