NUCLEOLAR ORGANIZER REGIONS IN PITUITARY-GLAND ADENOMAS


BAYINDIR C., DOGAN O., UNAL F., DERVISOGLU S.

CYTOPATHOLOGY, cilt.3, sa.4, ss.223-229, 1992 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 3 Konu: 4
  • Basım Tarihi: 1992
  • Doi Numarası: 10.1111/j.1365-2303.1992.tb00512.x
  • Dergi Adı: CYTOPATHOLOGY
  • Sayfa Sayıları: ss.223-229

Özet

Nucleolar organizer regions are DNA segments concerned with the synthesis of ribosomal RNA (rRNA). Some specific proteins related to NORs can be demonstrated by a silver technique and are then referred to as Ag-NORs. The mean number of Ag-NORs per cell has been used as a marker of cell proliferation in recent years and there is some evidence to suggest that Ag-NOR counts can be used to differentiate between normal and neoplastic cells.