Melatonin ameliorates oxidative damage in hyperglycemia-induced liver injury


Korkmaz G. G. , Uzun H. , Cakatay U. , Aydin S.

CLINICAL AND INVESTIGATIVE MEDICINE, cilt.35, 2012 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 35 Konu: 6
  • Basım Tarihi: 2012
  • Dergi Adı: CLINICAL AND INVESTIGATIVE MEDICINE

Özet

Purpose: Melatonin (N-acetyl-5-methoxy-tryptamine) is synthesized mainly by the pineal gland and its antioxidant properties have been demonstrated both in short and long term studies. Our aim was to clarify the effects of hyperglycemia and to administer melatonin on lipid peroxidation, protein oxidation and oxidative DNA damage in rat.