The aim of this study was to investigate the effects of using different commercial feeds on growing performance and fatty acid profile of sea bream and sea bass aquacultured in net cages. Four different fish companies (i.e. 4 experimental groups) were given different commercial feeds (extruded fish feed) to be used regularly for 480 days. Omega-3 [eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA)] values of feeds for groups 1, 2, 3, and 4 were 11.81%, 14.23%, 7.69%, and 12.01%, respectively. When compared, omega-3 components in sea bass were higher than in sea bream. EPA and DHA fatty acids were 12.53% in sea bass and 11.06% in sea bream. When fatty acid contents of feeds were compared with fatty acid levels of sea bream and sea bass, it was determined that the total monounsaturated fatty acid (Sigma MUFA) level was the highest in sea bass (38.13%) and sea bream fishes (39.12%) in group 3 given fish meal that had the highest Sigma MUFA content (38.05%). It was observed that the fatty acid profile of the sea bream and sea bass reflected the fatty acid contents of the feeds used in their feeding.