Reducing the pathogen burden and promoting healing with polyhexanide in non-healing wounds: a prospective study


Ceviker K., Canikoglu M., Tatlioglu S., Bagdatli Y.

JOURNAL OF WOUND CARE, cilt.24, ss.582-586, 2015 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 24 Konu: 12
  • Basım Tarihi: 2015
  • Doi Numarası: 10.12968/jowc.2015.24.12.582
  • Dergi Adı: JOURNAL OF WOUND CARE
  • Sayfa Sayıları: ss.582-586

Özet

Objective: Polyhexamethylene biguanide (PHMB) is a novel wound antiseptic solution that has a broad antimicrobial spectrum and wound healing promoting effect, with minimal side effects. The aim of present study was to demonstrate the efficacy of the PHMB on the bacterial burden of non-healing wounds, the reduction in wound size or closure of the wound in comparison to Ringer's lactate solution (RLS) after 21 days of wound dressing. A second objective was to investigate the differences in the C-reactive protein (CRP) levels and white blood cell (WBC) counts between the two groups.