Transfusion-related acute lung injury following coronary artery bypass graft surgery

Bitargil M., Arslan C., Basbug H. S. , Gocer H., Gunerhan Y., Bekov Y. Y.

PERFUSION-UK, cilt.30, ss.626-628, 2015 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 30 Konu: 8
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1177/0267659114568367
  • Dergi Adı: PERFUSION-UK
  • Sayfa Sayısı: ss.626-628


Blood transfusion is sometimes a necessary procedure during or following coronary artery bypass graft (CABG) surgery. However, transfusion-related acute lung injury (TRALI)/possible TRALI is a rare and fatal complication and characterized by acute hypoxemia and non-cardiogenic pulmonary edema that occurs within 6 hours following a transfusion. Anti-leukocyte antibodies or, possibly, other bioactive substances cause inflammation and capillary endothelial destruction in susceptible recipients' lungs. Prompt diagnosis and mechanical ventilatory support are important. A successful treatment of two male patients following CABG surgery, compatible with TRALI/possible TRALI, is presented here.