Antiviral properties of caffeic acid phenethyl ester and its potential application

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ERDEMLI H. K. , Akyol S., Armutcu F. , Akyol O.

JOURNAL OF INTERCULTURAL ETHNOPHARMACOLOGY, cilt.4, ss.344-347, 2015 (ESCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 4 Konu: 4
  • Basım Tarihi: 2015
  • Doi Numarası: 10.5455/jice.20151012013034
  • Sayfa Sayıları: ss.344-347


Caffeic acid phenethyl ester (CAPE) is found in a variety of plants and well-known the active ingredient of the honeybee propolis. CAPE showed anti-inflammatory, anticarcinogenic, antimitogenic, antiviral, and immunomodulatory properties in several studies. The beneficial effects of CAPE on different health issues attracted scientists to make more studies on CAPE. Specifically, the anti-viral effects of CAPE and its molecular mechanisms may reveal the important properties of virus-induced diseases. CAPE and its targets may have important roles to design new therapeutics and understand the molecular mechanisms of virus-related diseases. In this mini-review, we summarize the antiviral effects of CAPE under the light of medical and chemical literature.