The role of "Integrated Pulmonary Index" monitoring during morphine-based intravenous patient-controlled analgesia administration following supratentorial craniotomies: a prospective, randomized, double-blind controlled study


Akcil E. F. , Dilmen O. K. , VEHID H. E. , Yentur E. , Tunali Y.

CURRENT MEDICAL RESEARCH AND OPINION, cilt.34, ss.2009-2014, 2018 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 34 Konu: 11
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1080/03007995.2018.1501352
  • Dergi Adı: CURRENT MEDICAL RESEARCH AND OPINION
  • Sayfa Sayısı: ss.2009-2014

Özet

Objective: Morphine is commonly used in post-operative analgesia, but opioid-related respiratory depression causes a general reluctance for its use. The "Integrated Pulmonary Index" is a tool calculated from non-invasively obtained respiratory and hemodynamic parameters. The aim of this prospective, randomized, double blind, and placebo-controlled study is to determine a more safe and effective dose for morphine in patient-controlled analgesia following supratentorial craniotomy using the "Integrated Pulmonary Index".