Expression of MMP-1, MMP-9 and TIMP-2 in prostate carcinoma and their influence on prognosis and survival


Ozden F., Saygin C., Uzunaslan D., Onal B. , Durak H., Aki H.

JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, cilt.139, ss.1373-1382, 2013 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 139 Konu: 8
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1007/s00432-013-1453-x
  • Dergi Adı: JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
  • Sayfa Sayısı: ss.1373-1382

Özet

Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) participate in tumorigenesis, and their association with disease outcome is highly controversial. The present study investigates the influence of MMP-1, MMP-9 and TIMP-2 on different clinicopathologic variables and disease-free survival (DFS) of patients with prostate carcinoma.