Intrathecal methotrexate-induced acute cerebellar syndrome

Ferhanoglu B., Ongoren S. , Ar C., Uzel B., Forta H., Necioglu D.

ANNALS OF HEMATOLOGY, cilt.82, ss.241-243, 2003 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 82 Konu: 4
  • Basım Tarihi: 2003
  • Doi Numarası: 10.1007/s00277-003-0618-0
  • Dergi Adı: ANNALS OF HEMATOLOGY
  • Sayfa Sayıları: ss.241-243

Özet

Intrathecal application of chemotherapeutics has been the mainstay of central nervous system prophylaxis in acute lymphoblastic leukemia treatment. We describe a patient who developed acute cerebellar syndrome after prophylactic intrathecal methotrexate administration and recovered spontaneously. To our knowledge, this is the first case of methotrexate-related acute cerebellar syndrome.