The value of serum prostate specific antigen and other parameters in detecting bone metastases in prostate cancer

Ataus S., Çitçi A., Alici B., Önder A., SÖNMEZOĞLU K. , Erözenci A., ...Daha Fazla

International Urology and Nephrology, cilt.31, sa.4, ss.481-489, 1999 (SCI Expanded İndekslerine Giren Dergi) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 31 Konu: 4
  • Basım Tarihi: 1999
  • Doi Numarası: 10.1023/a:1007163227968
  • Dergi Adı: International Urology and Nephrology
  • Sayfa Sayıları: ss.481-489


The cut-off value of serum prostate-specific antigen (PSA) level in prediction of bone metastases and the correlation of serum PSA with the clinical stage, grade, score and the rate of bone metastases have been investigated in cases of prostate cancer (PCa). The study population consisted of 160 patients with histologically proven PCa between April, 1993 and August, 1996. The negative predictive value and the sensitivity were the highest (94%) in patients with a serum PSA value less than 10 ng/ml. We claim that in patients with PSA values less than 10 ng/ml whole body bone scan is not necessary.