Purpose: To investigate the effect of Buzzy (R) and ShotBlocker (R) on reducing pain induced by intramuscular penicillin injections in children, Methods: This was a randomized controlled study. A total of 150 Turkish children aged 7 similar to 12 years who presented to our pediatric emergency clinic and met the inclusion criteria were recruited. The children were randomly assigned to each group (control=50, Buzzy (R)=50, ShotBlocker (R)=50), Data were collected using an information form, the State-Trait Anxiety Inventory for Children, Visual Analog Scale, and Faces Pain Scale-Revised. Results: The children in the control group had significantly higher pain scores during the penicillin injection than the children in the ShotBlocker (R) and Buzzy (R) groups. The children in the Buzzy (R) group had significantly less pain than the children in both the ShotBlocker (R) and control groups (p<.001). Conclusion: Buzzy (R) was more effective compared with ShotBlocker (R) in this study.