Evaluation of classification criteria for juvenile-onset spondyloarthropathies

KASAPCOPUR O. , DEMIRLI N., OZDOGAN H. A. , APELYAN M., Caliskan S. , SEVER L., ...Daha Fazla

RHEUMATOLOGY INTERNATIONAL, cilt.25, ss.414-418, 2005 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 25 Konu: 6
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1007/s00296-004-0460-2
  • Sayfa Sayıları: ss.414-418


Objective: The aim of this study was to investigate the adequacy of the following criteria for the classification of juvenile-onset spondyloarthropathies (JSpA): European Spondyloarthropathy Study Group criteria ( ESSGCr) and Amor criteria (ACr) ( proposed for adult SpA), Garmisch-Partenkirchen ( G-PCr), seronegative enthesopathy and arthropathy syndrome (SEACr), and atypical spondyloarthropathies classification criteria (ASpCr) ( proposed for JSpA). Methods: Sixty-two patients with JSpA ( 48 male and 14 female) and 64 with juvenile idiopathic arthritis ( 27 male and 37 female) ( excluding enthesitis-related and psoriatic arthritis) were enrolled in the study group. Twenty-nine of the patients with JSpA were diagnosed with definite JSpA and the remaining 35 with undifferentiated JSpA. One hundred six patients in the study group were evaluated by one investigator, who was unaware of the diagnosis, according to the following: ESSGCr, ACr, GPCr, ASpCr, and SEACr. Results: Analysis of the patients diagnosed with JSpA showed 83.9%, 82.3%, 95.2%, 61.3%, and 62.9% sensitivity and 87.5%, 95.3%, 78.1%, 98.4%, and 92.2% specificity for the ESSGCr, ACr, G- PCr, ASpCr, and SEACr sets, respectively. Conclusion: None of the criteria evaluated above is sufficient for the classification of JSpA. There is a definite need for a new set of criteria with high specificity and sensitivity for early recognition and classification.