A Splenic Marginal Zone Lymphoma Case Presenting with Cyanosis, Spider Angiomas, and Polycythemia


Creative Commons License

Altunoglu E. G. , Ar M. C. , Tuzuner N., Saribeyoglu K.

ISTANBUL MEDICAL JOURNAL, cilt.16, ss.158-161, 2015 (ESCI İndekslerine Giren Dergi) identifier

  • Cilt numarası: 16 Konu: 4
  • Basım Tarihi: 2015
  • Doi Numarası: 10.5152/imj.2015.38233
  • Dergi Adı: ISTANBUL MEDICAL JOURNAL
  • Sayfa Sayıları: ss.158-161

Özet

Splenic marginal zone lymphoma (SMZL) is an indolent cancer classified among low-grade B-cell lymphomas in the World Health Organization (WHO) classification. The major characteristics of SMZL are splenomegaly, villous cytoplasmic protrusions of the lymphocytes in peripheral blood, anemia, and/ or thrombocytopenia. The involvement of various organs, particularly the bone marrow or liver, can be frequently observed. SMZL has been reported to be associated with hepatitis C infection. The course of the disease is generally indolent, but aggressive behavior may be observed in a minority of patients. Here, we report a 43-year-old male hepatitis B virus carrier who presented with abdominal distension, multiple spider angiomas on the skin, and central cyanosis, leading to a diagnosis of SMZL.