Effects of Tianeptine Pretreatment on Stress-Induced Trace Element Alterations in Rats


Karakoc Y., KASAR M., Mengi M., YILDIRIM E. A. , Yurdakos E., Barutcu U. B.

KLINIK PSIKOFARMAKOLOJI BULTENI-BULLETIN OF CLINICAL PSYCHOPHARMACOLOGY, cilt.19, 2009 (SCI İndekslerine Giren Dergi) identifier

  • Cilt numarası: 19
  • Basım Tarihi: 2009
  • Dergi Adı: KLINIK PSIKOFARMAKOLOJI BULTENI-BULLETIN OF CLINICAL PSYCHOPHARMACOLOGY

Özet

Introduction: Although the alterations in trace elements levels were shown in chronically restrainted rats, the association between stress-induced changes in trace element levels and the effects of psychopharmacological agents has not been well documented yet. Tianeptine has been a widely used antidepressant in experimental studies investigating stress related behavioral changes. In this study, we aimed to search the effects of tianeptine pretreatment on stress-induced trace element alterations in rat brain.