Soluble Lectin-Like Oxidized LDL Receptor 1 as a Possible Mediator of Endothelial Dysfunction in Patients With Metabolic Syndrome


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Civelek S., Kutnu M., Uzun H. , Erdenen F., Altunoglu E., Andican G., et al.

JOURNAL OF CLINICAL LABORATORY ANALYSIS, cilt.29, ss.184-190, 2015 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 29 Konu: 3
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1002/jcla.21748
  • Dergi Adı: JOURNAL OF CLINICAL LABORATORY ANALYSIS
  • Sayfa Sayısı: ss.184-190

Özet

BackgroundMetabolic syndrome (MetS) defines a well-known cluster of metabolic disturbances associated with an increased risk of cardiovascular disease and diabetes. The aim of this study was to examine the distribution of soluble lectin-like oxidized low-density lipoprotein (LDL) receptor-1 (sLOX-1) levels in patients with MetS, possible association of sLOX-1 with oxidized LDL (oxLDL), endothelial nitric oxide synthase (eNOS), nitric oxide (NOx), endothelin-1 (ET-1), paraoxonase 1 (PON1), and arylesterase (ARE) activities, and these parameters compared with healthy controls.