Vascular Cell Adhesion Molecule 1, Intercellular Adhesion Molecule 1, and Cluster of Differentiation 146 Levels in Patients with Type 2 Diabetes with Complications


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HOCAOGLU-EMRE F. S. , Saribal D. , Yenmis G., Guvenen G.

ENDOCRINOLOGY AND METABOLISM, cilt.32, ss.99-105, 2017 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 32 Konu: 1
  • Basım Tarihi: 2017
  • Doi Numarası: 10.3803/enm.2017.32.1.99
  • Dergi Adı: ENDOCRINOLOGY AND METABOLISM
  • Sayfa Sayıları: ss.99-105

Özet

Background: Type 2 diabetes mellitus (T2DM) is a multisystemic, chronic disease accompanied by microvascular complications involving various complicated mechanisms. Intercellular adhesion molecule 1 (ICAM-1), vascular cell adhesion molecule 1 (VCAM-1), and cluster of differentiation-146 (CD146) are mainly expressed by endothelial cells, and facilitate the adhesion and transmigration of immune cells, leading to inflammation. In the present study, we evaluated the levels of soluble adhesion molecules in patients with microvascular complications of T2DM.