Systemic lupus erythematosus due to Epstein-Barr virus or Epstein-Barr virus infection provocating acute exacerbation of systemic lupus erythematosus?

Kasapcopur O. , Ergul Y., Kutlug S. , Candan C., Camcioglu Y. , Arisoy N.

RHEUMATOLOGY INTERNATIONAL, cilt.26, ss.765-767, 2006 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 26 Konu: 8
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1007/s00296-005-0063-6
  • Sayfa Sayıları: ss.765-767


Systemic lupus erythematosus (SLE) is a rheumatologic disease characterized by an inflammatory destruction of the target organ systems of the body in an unknown way by autoantibodies formed against self-antigens. Infectious agents like Epstein-Barr virus (EBV), cytomegalovirus and parvovirus B19 may have a role in the occurrence or the exacerbation of the SLE. In this report, the clinical follow-up of a 14-year-old girl diagnosed with SLE following an EBV infection with bicytopenia, lymphadenomegaly and hepatomegaly is discussed. This case could support the role of viral infections in the etiology of SLE.