Questioning the discontinuation of long half life oral hypoglycaemic drugs before surgery

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Güngör G. , Sutaş Bozkurt A. P. , Buluc S.

The Scandinavian Society of Anaesthesiology and Intensive Care Medicine 3rd SSAI Congress, Reykjavik, Iceland, 10 - 12 June 2015, pp.1-2

  • Publication Type: Conference Paper / Summary Text
  • City: Reykjavik
  • Country: Iceland
  • Page Numbers: pp.1-2


Free Paper Session 18 – General Anaesthesia II

O18-01 Questioning the discontinuation of long half-life oral hypoglycaemic drugs before surgery? Gurcan Gungor1, Pervin Bozkurt Sutas1, Cigdem Heyik2, Berna Asan3, Yesim Cokay Abut4, Sibel Buluc4, Ozlem Gul1 1Cerrahpasa Medical Faculty/Istanbul University, Turkey, 2Inebolu Government Hospital, Turkey, 3Kurtalan Government Hospital, Turkey, 4Istanbul Training and Education Hospital, Turkey

Some of the oral hypoglycaemic drugs (OHD) (long half- life sulfonylurea etc.) are advised to be discontinued the day before surgery in Type II diabetic patients (1). The aim of this study is to prove that the guideline regarding discontinuation of some OHDs before surgery requires revision. Material and Methods: Twenty-three patients who were on OHD and undergoing eye surgery under general anaesthesia had participated in the study following informed consent and Ethics approval in 2012- 2015 calendar years. All patients were asked to discontinue OHD the day before surgery. Ten patients discontinued OHD and 13 patients continued despite the order to stop. HbA1c preoperatively and blood glucose (BG), arterial pressures (systolic and diastolic;SAP-DAP), heart rate (HR) and SpO2 were recorded the day before and morning of surgery, intra-operative 30th and postoperative 10th and 90th min. Student’s t test and ANOVA for repeated measurements were applied. Results: Patients’ ages were between 39–82 years and on OHD for 1–20 years. There were no significant differences in HbA1c, BG, SAP-DAP, HR and SpO2 between groups Table 1. Conclusion: The fluctuations in blood glucose were significant in patients stopping OHD the day before minor surgery. The fear of hypoglycaemia is not proved so that long half-life OHDs should not be interrupted prior to surgery.

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© 2015 The Authors. Acta Anaesthesiologica Scandinavica © The Acta Anaesthesiologica Scandinavica Foundation Acta Anaesthesiologica Scandinavica, 59 (Suppl. 121