Mammillothalamic and Mammillotegmental Tracts as New Targets for Dementia and Epilepsy Treatment


Balak N., Balkuv E., Karadag A., Basaran R., BİÇEROĞLU H., Erkan B., ...More

WORLD NEUROSURGERY, vol.110, pp.133-144, 2018 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 110
  • Publication Date: 2018
  • Doi Number: 10.1016/j.wneu.2017.10.168
  • Title of Journal : WORLD NEUROSURGERY
  • Page Numbers: pp.133-144
  • Keywords: Amnesia, Brain, Epilepsy, Mammillary body efferents, Memory, Neuroanatomy, DEEP BRAIN-STIMULATION, DIFFUSION TENSOR TRACTOGRAPHY, REFRACTORY PARTIAL EPILEPSY, VENTRAL TEGMENTAL NUCLEUS, ANTERIOR THALAMIC NUCLEI, TEMPORAL-LOBE EPILEPSY, HEAD DIRECTION SIGNAL, MAMMILLARY BODY, RESPONSIVE NEUROSTIMULATION, ELECTRICAL-STIMULATION

Abstract

BACKGROUND: Recently, neuromodulation through deep brain stimulation (DBS) has appeared as a new surgical procedure in the treatment of some types of dementia and epilepsy. The mammillothalamic and mammillotegmental tracts are involved among the new targets. To our knowledge, a review article focused specifically on these mammillary body efferents is lacking in the medical literature. Their contribution to memory is, regrettably, often overlooked.