Synthesis of novel 1,4-naphthoquinone derivatives: antibacterial and antifungal agents


Ibis C., Tuyun A. F. , Bahar H., Ayla S. , Stasevych M. V. , Musyanovych R. Y. , et al.

MEDICINAL CHEMISTRY RESEARCH, cilt.22, ss.2879-2888, 2013 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 22 Konu: 6
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1007/s00044-012-0300-y
  • Dergi Adı: MEDICINAL CHEMISTRY RESEARCH
  • Sayfa Sayısı: ss.2879-2888

Özet

A novel series of substituted 1,4-naphthoquinone derivatives was synthesized and evaluated for antibacterial and antifungal activity. The structures of the novel products were characterized by spectroscopic methods. Among the tested compounds, 3a and 9 are the most effective compounds against M. luteum as potent antibacterial and C. tenuis and A. niger as potent antifungal. These two compounds are promising as biologically active compounds.