Dietary curcumin and capsaicin: Relationship with hepatic oxidative stress and apoptosis in rats fed a high fat diet


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Tanrıkulu-Küçük S., Basaran-Kucukgergin C., Söğüt İ., Tunçdemir M. , Dogru-Abbasoglu S., Seyithanoğlu M., et al.

ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE, cilt.28, ss.1013-1020, 2019 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 28
  • Basım Tarihi: 2019
  • Doi Numarası: 10.17219/acem/94145
  • Dergi Adı: ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE
  • Sayfa Sayısı: ss.1013-1020

Özet

Background. Apoptosis plays a major role in fatty liver disease. High-fat diets are related to the onset of fatty liver disease and hepatic oxidant-antioxidant imbalance. Curcumin and capsaicin are somewhat beneficial in reducing hepatic triglycerides; this is most likely because they are known to downregulate reactive oxygen species (ROS) and apoptosis.