Paradoxal reaction with midazolam (3 case reports)

Salihoǧlu Z. , Demiroluk Ş., Köse Y., Karaca S.

Anestezi Dergisi, cilt.10, ss.69-71, 2002 (Diğer Kurumların Hakemli Dergileri) identifier

  • Cilt numarası: 10
  • Basım Tarihi: 2002
  • Dergi Adı: Anestezi Dergisi
  • Sayfa Sayıları: ss.69-71


We report 3 cases of paradoxical reaction to midazolam after being used for premedication. The picture was characterized by a marked aggressiveness and agitation. In one case the reaction was treated with general anesthesia, whereas in the other two patients the clinical picture was rapidly reversed by administration of fentanyl. We describe the possible causative mechanisms of this reaction as well as their treatment.