Rapidly Progressive Thyroid Mass: Amyloid Goiter

Ibrahimov M., Yilmaz M. , Kilic E., Akil F., Rasidov R., Karaman E.

JOURNAL OF CRANIOFACIAL SURGERY, cilt.23, sa.6, 2012 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 23 Konu: 6
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1097/scs.0b013e31825cef34


Amyloidosis is a disease of unknown etiology characterized by the accumulation of an amorphous proteinaceous material in various organs and tissues of the body. Amyloid goiter is an exceedingly rare pathologic condition due to massive amyloid infiltration of the thyroid tissue. Amyloid goiter occurs in association with both primary and secondary systemic amyloidosis, more commonly in the latter. Preoperatively, it simulates a multinodular goiter, and surgical intervention is often necessary to establish a diagnosis and to relieve compressive symptoms of a neck mass. We present the case of an 85-year-old female patient who presented with a rapidly enlarging goiter. Histologic examination confirmed amyloid goiter.