De novo X/X translocation in a patient with secondary amenorrhea.


Tarkan Y. , Hacıhanefıoglu S., Sılahtaroglu A., Devıren A., Topcuoglu D., Cenanı A.

Hereditas, cilt.122, ss.19-23, 1995 (SCI Expanded İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 122
  • Basım Tarihi: 1995
  • Doi Numarası: 10.1111/j.1601-5223.1995.00019.x
  • Dergi Adı: Hereditas
  • Sayfa Sayıları: ss.19-23

Özet

A 46,X,t(X;X) (qter --> p22::p22 --> qter) karyotype was found in the chromosome analysis of a 22 years old female patient with secondary amenorrhea. Further analysis with fluorescence in situ hybridization indicated that the marker chromosome had one active and one inactive centromere originating from the X chromosome. RBG-banding showed that the derivative X chromosome was preferentially inactivated in cultured lymphocytes.