Genetic Variations in Tumor Necrosis Factor Alpha, Interleukin-10 Genes, and Migraine Susceptibility

Creative Commons License

Ates O., Kurt S., Altinisik J. , Karaer H., Sezer S.

PAIN MEDICINE, cilt.12, ss.1464-1469, 2011 (SCI İndekslerine Giren Dergi)


Objectives. Migraine is a very common headache disorder and pathogenesis of the disease is still largely unknown. Cytokine genes have been implicated in migraine susceptibility. The present study was designed to explore the associations of polymorphisms in the tumor necrosis factor alpha (TNF-alpha), interleukin-10 (IL-10) gene, and IL-10 haplotypes in Turkish migraine patients.