Association of clinicopathological features with E-cadherin (CDH1) gene-160 C>A promoter polymorphism in Turkish colorectal cancer patients

BAHADIR A., Eral G., Budak M., Shimamoto F., Korpinar M. A. , Erdamar S., et al.

Journal of Cancer Research and Therapeutics, cilt.15, ss.26-31, 2019 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 15 Konu: 1
  • Basım Tarihi: 2019
  • Doi Numarası: 10.4103/jcrt.jcrt_1277_16
  • Dergi Adı: Journal of Cancer Research and Therapeutics
  • Sayfa Sayısı: ss.26-31


Background and Aim of Study: The role of E-cadherin (CDH1) gene-160 C>A (rsl 6260) promoter polymorphism in colorectal cancer (CRC) still remains inconclusive. The aim of this study is to investigate the associations between the CDH1 -160 C>A polymorphism with the susceptibility and clinicopathological development of CRC in the Turkish patients. To our knowledge, this is the first report examining the role of CDH1 polymorphism in Turkish CRC patients.