Association Between Level of Hepatitis D Virus RNA at Week 24 of Pegylated Interferon Therapy and Outcome


KESKİN O., Wedemeyer H., Tuzun A., Zachou K., Deda X., Dalekos G. N. , ...More

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, vol.13, no.13, pp.2342-2351, 2015 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 13 Issue: 13
  • Publication Date: 2015
  • Doi Number: 10.1016/j.cgh.2015.05.029
  • Title of Journal : CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
  • Page Numbers: pp.2342-2351
  • Keywords: Chronic Delta Hepatitis, Pegylated Interferon Treatment, Treatment Outcome Prediction, On-Treatment HDV RNA, CHRONIC DELTA-HEPATITIS, PEGINTERFERON ALPHA-2A, KINETICS, INTERLEUKIN-28B, POLYMORPHISMS, RIBAVIRIN, EFFICACY, HBSAG, DRUG

Abstract

BACKGROUND & AIMS: Interferon is the only effective treatment for chronic hepatitis D virus (HDV) infection. No rules have been set for stopping treatment based on viral kinetics. We analyzed data from an international study of hepatitis D treatment to identify factors associated with outcomes of pegylated interferon treatment, with and without adefovir.