Evaluation of lipid peroxidation, oxidant/antioxidant status, and serum nitric oxide levels in alopecia areata


Koca R., ARMUTCU F., Altinyazar C., Gurel A.

MEDICAL SCIENCE MONITOR, vol.11, no.6, 2005 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 11 Issue: 6
  • Publication Date: 2005
  • Title of Journal : MEDICAL SCIENCE MONITOR

Abstract

Background: The pathophysiology of alopecia areata (AA) has not been clearly defined; however, it appears as a tissue-restricted autoimmunne disease mediated by T lymphocytes. Immunohistochemical studies have shown peri- and infra-follicular inflammatory infiltrate which damages hair follicles. We. analyzed the role of lipid peroxidation and oxidant-antioxidant enzymes in the pathogenesis of AA.