Laboratory investigations reflecting liver disease are commonly termed as liver function tests. Although this term is misnomer, it has been traditionally continued to use by clinicians. Meanwhile, some terms such as liver panels, liver biochemistries or hepatic profiles have been used. An alternative term is routine tests of the liver. This article reviews routine tests for liver disease including serum aminotransferases, alkaline phosphatase, gamma glutamyl transferase, bilirubin, albumin and prothrombin time.