The Effect of Anti-Human Leukocyte Antigen, Anti-Major Histocompatibility Complex Class 1 Chain-Related Antigen A, and Anti-Glutathione Transferase-T1 Antibodies on the Long-Term Survival of Renal Allograft


Akgul S. U. , Oguz F. S. , Caliskan Y., Kekik C., Cagatay P. , Turkmen A., ...Daha Fazla

TRANSPLANTATION PROCEEDINGS, cilt.45, ss.890-894, 2013 (SCI İndekslerine Giren Dergi) identifier identifier identifier

Özet

Background. One of the most important mechanisms of allograft rejection is the production of donor-specific antibodies (DSA). Anti-major histocompatibility complex class-I chain-related antigen A (MICA) and anti-glutathione S transferase-T1 (GSTT1) antibodies cause graft dysfunction and reduce graft survival. The aim of this study was to examine the effects of anti-human leukocyte antigen class I-II, anti-MICA, and anti-GSTT1 antibodies in development of antibody-mediated rejection.