The Effect of ZAP-70 Expression on Disease Progression in Early-Stage (Binet A) B-CLL Patients


URE U., Ar M. C. , Baslar Z. , Soysal T. , Ongoren S. , Gulseven M. , et al.

TRAKYA UNIVERSITESI TIP FAKULTESI DERGISI, cilt.26, ss.317-321, 2009 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 26 Konu: 4
  • Basım Tarihi: 2009
  • Dergi Adı: TRAKYA UNIVERSITESI TIP FAKULTESI DERGISI
  • Sayfa Sayısı: ss.317-321

Özet

Objectives: Chronic lymphocytic leukemia (CLL) is a heterogeneous disease with various clinical findings. Prognostic markers predicting the clinical outcome in early-stage CLL would play a major role in disease management. Various studies have shown that zeta-associated protein 70 (ZAP-70) provides significant prognostic information This retrospective, single-centre study evaluates the effect of ZAP-70 on disease progression in early-stage B-CLL