Genetic alterations in human prostate cancer: A review of current literature


Ozen M. , Pathak S.

ANTICANCER RESEARCH, cilt.20, ss.1905-1912, 2000 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 20
  • Basım Tarihi: 2000
  • Dergi Adı: ANTICANCER RESEARCH
  • Sayfa Sayısı: ss.1905-1912

Özet

We review the literature dealing with genetic alterations in human prostate cancer. We also discuss genetic predisposition and the roles of various proto-oncogenes and tumor-suppressor genes in prostate cancer initiation, progression, and metastasis. The role of telomere dynamics in prostate cancer metastasis and the induction of apoptosis is also briefly discussed.