The reactions of polyhalogenated-2-nitro-1,3-butadiene with alkylthio, thiomorpholine and piperazine derivatives


Ibis C., Deniz N. G.

INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, cilt.47, ss.1407-1413, 2008 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 47 Konu: 9
  • Basım Tarihi: 2008
  • Dergi Adı: INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY
  • Sayfa Sayısı: ss.1407-1413

Özet

Mono(thio)substituted-1,3-nitrodiene compounds 3a-c give 5a, 5e, 7a, 7c, 9a, 9c, 11a, 11c, 13a, 13b with thiomorpholine 4 and piperazine derivatives 6, 8, 10, 12. The new compound 3a is synthesized from reaction of 1 with 2a. The compound 7b crystallizes in the monolinic crystal system (space group P2(1/n)) with the n-butyl group attached to S1 and C2Cl3 group disordered. The butadiene unit is not completely planar as can be expected if the two double bonds are fully Conjugated. The structure has been solved by direct methods by using SHELXS-97 program and refined by using SHELXL-97 to the residul index R(1)=0.048.